ADNOWELL is an innovation in the field of natural antidepressants. It combats depression by boosting mood and reducing depression symptoms naturally. S- Adenosyl Methionines (SAMe) are the best natural remedies for depression. Their maximum concentration is found in brain and liver. They are safe, fast-acting and the most effective natural antidepressant. It is also an anti-oxidant that protects brain cells from damage.